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癌症預防的新希望: 深海礦物質

2020-10-16
517
感謝郭教授與臺灣深層海水資源利用學會授權台肥季刊轉載
文/郭家驊 特聘教授
2020年6月份在美國學術期刊「癌症醫學期刊《Cancer Medicine》」的封面故事報導一則台灣本土的腫瘤研究(資料來源:https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.3028),這個研究係由科技部、台肥集團・台海生技與台北市立大學聯合贊助的長期自由型計畫。
研究結果發現,在花蓮外海662米取得的脱鹽深層海水,可明顯讓中老年自然發展出來的腫瘤機率近乎減半。這些動物在達到成年後即終身飲用,對照組為一般的水或11%的糖水。糖水則相對提高腫瘤發展。雖然動物壽命並沒有因飲用深層海水改變,這個研究結果產生了一個新的腫瘤研究方向,並讓我們了解礦物質與微量元素的多元性,可能是影響中年腫瘤發生的重要原因。此研究結果之所以重要,是由於過去全球大部分的腫瘤研究是使用年輕動物植入篩選高頑強性的腫瘤,這些研究與人類實際上大部分是因老年才自然發展的腫瘤有很大的差異。因此,這個剛發表的研究結果是極少觀察老年自發性腫瘤的研究,更貼近真實的應用面。
Cancer Medicine,Volume 9, Issue 11 Pages: i-ii, 3635-4036, First Published: 10 June 2020
深海礦物質方面的研究成果,在日本一個早期研究發現與淺海的礦物質相比在鈣、鎂、鈉、鉀等濃度並無差異。然而在心血管保護的效果上深海礦物質比淺海礦物質明顯較佳。這個早期的研究成果顯示,未被淺海藻類光合作用所吸收,因而被保留下來的微量元素,可能為重要的營養關鍵因素。微量元素因濃度太低人類測量技術目前尚未克服難以測得,因此在營養學的研究文獻、教科書所刊載的知識不是非常充足。
 
在上述腫瘤研究中,另一個特別的發現是終身飲用662米深層海水的動物在中年時身體自然活動量偏高、体重增長較慢。其內在的原因並不清楚。然而,這個研究結果在人體實驗上也被證實過,短時間速度型的運動表現與反應明顯改善。特別對中年人(48歲),運動過程大腦獲得血液供應的反應速度明顯加快,這顯示了662米深層海水的作用可能是在改善大腦與全身血管的功能。耐力部分的研究結果則無一致性,662米深海礦物質的作用可能較小。
Lower tumorigenesis without life extension in rats receiving lifelong deep ocean waters研究截圖,Cancer Medicine,Volume 9, Issue 11 Pages: i-ii, 3968
人類目前對於深海礦物質與微量的研究相度不足。演化學理論目前已指向陸上動物的祖先是由海洋缺乏陽光的地熱環境中逐漸演化出來。如果確實如此,陸地上的生物是遠離有利生存的自然環境,我們將可能是那些少數存活者的後代。因此,補充662米深層海水可彌補因演化移地所造成的先天營養缺乏,對我們的身體帶來一些正面的健康效益。這些水份在脫鹽後亦可用來作為灌溉農田施肥的原料,直接帶給人體好處。
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[轉載資訊]本文轉載自臺灣深層海水資源利用學會會訊 第四期 2020年10月出版
[臺灣深層海水資源利用學會簡介]
臺灣深層海水資源利用學會為依法設立非以營利為目的之社會團體,以推動深層海水利用之學術發展、研究成果之評價與推廣、促進資訊流通、國際合作以及會員交流為宗旨。
為了有效利用全人類共享的天然資源─深層海水,有必要加強和提升與產業界、學術界以及政府組織之間的密切聯結,以促進推廣深層海水的研究應用。透過與國際間的合作研究與交流,深層海水已經成為海內外積極研究開發的海洋產業課題,國內各界也一直嚮往亟待成立一個能自由交流深層海水相關技術及研發的訊息,有鑑於此,結合了產學研各界成員,成立了「臺灣深層海水資源利用學會」,以促進國內深層海水產業發展,及增進各界相關領域人員交流與合作。

[歡迎報名參加]
2020深層海水國際研討會
研討會報名網站:https://sites.google.com/view/twdowa2020/
臺灣深層海水產業自發展以來,持續受到產官學研各界關注與支持,由點線至面逐步開展,可望為臺灣深層海水產業注入新動力。期許未來持續耕耘面對每一課題,拓展深層海水應用潛能,開創未來無限可能。
 
台海生技副總經理簡照人(左三)與臺北市立大學特聘教授兼體育學院院長郭家驊博士(左六)及研究團隊合影。/台海生技提供
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